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During this same period, tobacco imports to the USA from Indonesia, a leader in clove tobacco production, shifted from cigarettes to almost exclusively cigars

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since then, the prevalence of current and daily EC use has steadily increased

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Notably, the whole PBMCs or circulating immune cell subsets from the four healthy and asthmatic smoker/never-smoker groups did not differ in terms of IL-1-producing cell frequencies (Supplementary Fig

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